Publications

Representative Publications

  1. Chemosensitizing effect of Paris Saponin I on Camptothecin and 10-hydroxycamptothecin in lung cancer cells via p38 MAPK, ERK, and Akt signaling pathways. European Journal of Medicinal Chemistry. 2017, 125:760-769.
  2. 1,4-Addition Ugi Reaction Using Cyclic α,β-Unsaturated Ketone as Substrate. Organic Letters. DOI:10.1021/acs.orglett.6b02493
  3. Synthesis of Substituted Pyrroles via Copper-catalyzed Cyclization of Ethyl Allenoates with Activated Isocyanides. Chemistry – An Asian Journal. 2016, 11(15), 2121-2125.
  4. Total synthesis of 8-(6″-umbelliferyl)-apigenin and its analogs as anti-diabetic reagents. European Journal of Medicinal Chemistry. 2016, 112(21): 674-683.
  5. Inhibitory activity evaluation and mechanistic studies of tetracyclic oxindole derivatives as a-glucosidase inhibitors. European Journal of Medicinal Chemistry. 2016, 123: 365-378
  6. Paris Saponin I inhibit proliferation and promote apoptosis through down-regulating AKT activity in human non-small-cell lung cancer cells and inhibiting ERK expression in human small-cell lung cancer cells. RSC Advances. 2016, 6: 70816-70824
  7. Synthesis of multivalent difluorinated zanamivir analogs as potent antiviral inhibitors. Tetrahedron Letters. 57 (2016) 2579–258
  8. A Highly Practical and Convenient Halogenation of Fused Heterocyclic N-oxides. Tetrahedron. 2016, 72(38), 5762-5768
  9. Low toxic and high soluble camptothecin derivative e 2–47 effectively induces apoptosisof tumor cells in vitro, Biochemical and Biophysical Research Communications, 2016, 1:11-13.
  10. Synthesis and Anti-cancer Activity Evaluation of 5-(2-Carboxyethenyl)-isatin Derivatives. European Journal of Medicinal Chemistry. 2016, 112(1): 145-156.
  11. Synthesis, alpha-glucosidase inhibitory and molecular docking studies of prenylated and geranylated flavones, isoflavones and chalcones. Bioorganic & Medicinal Chemistry Letters, 2015, 25(20), 4567-4571.
  12. Total synthesis of (+/-)-Anastatins A and B. Tetrahedron Letters, 2015, 56(30), 4472-4475.
  13. Synthesis and Biological Evaluation of Novel Water-soluble poly-(ethylene glycol)-10-hydroxycamptothecin conjugates. Molecules, 2015, 20, 9393-9404.
  14. Preparation of Novel Pyrrolo[2,3-b]pyridine Derivatives via a New Concise Synthetic Approach. Bulletin of the Korean Chemical Society, 2015, 36, 1143-1147.
  15. Synthesis and antitumor activity evaluation of a novel series of xanthone derivatives. Journal of Asian Natural Products Research. 2015, 17(4): 377-383.
  16. Direct C-H iodination of 1,3-azoles catalysed by CuBr2 .Tetrahedron Letters. 2015, 56(3): 511-513.
  17. Synthesis and anti-cancer activity evaluation of novel prenylated and geranylated chalcone natural products and their analogs. European Journal of Medicinal Chemistry, 2015, 92, 439-448.
  18. Biochemical and Biophysical Research Communications. 2014, 450 (4): 1650-1655.
  19. Concise synthesis of prenylated and geranylated chalcone natural products by regiospecific iodination and Suzuki coupling reactions. Tetrahedron Letters. 2014, 55(4): 897-899.
  20. Design, synthesis and in vitro cytotoxicity evaluation of 5-(2-carboxyethenyl)isatin derivatives as anticancer agents. Bioorganic & Medicinal Chemistry Letters. 2014, 24 (2), 591-594.
  21. Regioselective iodination of flavonoids by N-iodosuccinimide under neutral conditions . Tetrahedron Letters, 2013, 54(47):6345-6348.